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As every muscle has a distinct pattern of ESC incorporation in a chimera, the values obtained from the 2 EDL muscles from the same animal (2 mice) were independently considered, and thus, n = 4 per chimeric category (10 30% and <5%).
Although the decrease in inclusion did not quite reach statistical significance for C10orf97 exon 5 in pectoral muscle, a significant decrease was found in thigh muscles from the same mice (41.4±1.8% in wild type versus 32.5±3.7% inclusion in Myo-CELFΔ-370 mice, P = 0.01).
As every muscle has a distinct pattern of iPSC incorporation in a chimera, the values obtained from the 2 EDL muscles from the same WT/mdx animal (n = 2) were independently considered, and thus, n = 4 per WT/mdx group [35].
Figures 8J and L show 3D reconstructions of the direct flight muscles from lmsS95/Df 2R exu2 and lmsS119/Df 2R exu2 flies, respectively, viewed from the inside like the control in Fig. 8H, and panels K and J depict these muscles from the same flies as viewed from the outside.
Such changes were not present in extradiaphragmatic muscles from the same patients or diaphragms of infants ventilated for 7 days or less [ 43].
On the other hand, the use of different muscles from the same pig could minimise the effects of environmental variation, which could exist between individuals.
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Signal intensities at the ROI were normalized to un-enhanced muscle from the same slice.
One would need to perform many more experiments to determine whether mdcs/pericytes from one muscle are more myogenic than the same cells from another muscle from the same individual, or whether age, sex or pathological status has an effect on number, location or activation status of resident stem or precursor cells.
TEM numbers in ischemic muscle are two-fold greater than normoxic muscle from the same patient.
Fat and muscle from the same axial locations were subjected to vigorous pipetting.
Another study, performed on paired samples of brain and skeletal muscle from the same patients, showed 3.1-fold more foci in cortical neurons than in muscle (13).
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