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However, the soleus muscle was spared from tumor-induced atrophy.
The insertion of the neurovascular bundle and a trapezoid region with a 3-mm long base at the insertion of the bundle and a 2-mm short base at the lateral margin of the soleus muscle was spared and 3 crushes were exerted proximal to this area in the manner described above.
In contrast to previously described whole soleus crush injuries (Bassaglia and Gautron 1995, Fink et al. 2003), the area of the neuromuscular junctions in the soleus muscle, a well-defined region at the midbelly of the muscle, was spared in order to create a model of a trauma selectively affecting the muscle fibers and the interstitial tissue without harming the main innervation of the organ.
Similar(57)
For example, oculopharyngeal muscular dystrophy is associated with severe atrophy restricted to FG fibers, while oxidative fibers in the soleus muscle are spared [49].
In the late-onset forms, caused by a partial enzyme deficiency, cardiac muscle is spared, but slowly progressive skeletal muscle weakness leads to wheelchair and ventilator dependence, and premature death from respiratory insufficiency [3].
Skeletal muscles are also involved in the ossification process; however, smooth muscle and cardiac muscle are spared [ 28].
Interestingly, the Soleus muscle showed a smaller, non significant decline in the fatigue time, indicating that resistance of this muscle is spared in cachexia.
Extraocular muscles were spared.
In an advanced stage, distal impairment may become apparent, but respiratory, bulbar, and facial muscles are spared.
The diaphragm, tongue and extraocular muscles are spared from FOP. Cardiac muscle and smooth muscle are not affected (Connor and Evans, 1982).
2 3 One case control study demonstrated that MV results in increased proteolysis and atrophy in the diaphragm muscle, while other skeletal muscles are spared.
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