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Matsakas, A. & Patel, K. Intracellular signalling pathways regulating the adaptation of skeletal muscle to exercise and nutritional changes.
The benefit of protein supplementation on the adaptive response of muscle to exercise training in older people is controversial.
However, environmental factors such as advanced age and chronic disease can also impair the adaptive response of muscle to exercise, or physically limit the ability of an individual to undertake exercise training regimens17.
Furthermore, Timmons et al.4 expressed doubts about the response of FNDC5 mRNA in human muscle to exercise, based on their previous and larger data sets, which showed no such response.
Other genes with potentially important roles in the adaptation of muscle to exercise, specifically in the processes of angiogenesis and cell proliferation, showed a similar response to exercise in older compared with younger subjects.
This gene is central to the adaptations of muscle to exercise by transcriptionally regulating this biological program.
Similar(42)
The present study describes the cellular and molecular adaptive mechanisms that are responsible for the plasticity of fast skeletal muscle to exercise-induced contractile activity.
Skeletal muscle adaptation to exercise training: AMP-activated protein kinase mediates muscle fiber type shift.
The few physiological situations in the adult where micro-vascular remodeling is required include the female menstrual cycle and skeletal muscle responding to exercise.
Such results highlight the importance of HIT in enhancing muscle tolerance to exercise by improving anaerobic capacity.
Adherence to exercise may be partly biologically and genetically moderated through metabolic regulatory pathways participating in skeletal muscle adaptation to exercise training.
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