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One of the greatest challenges for skeletal muscle tissue engineering is the integration of the functional engineered muscle tissue with the native tissues of the recipient.
While conventional muscle tissue engineering that is based on cell culture techniques for fabrication of engineered muscle constructs has been demonstrated both preclinically and clinically, the cell-based approach requires donor tissue biopsy and in vitro cell manipulation.
(A) Experimental design for muscle tissue engineering with ETV2-iEC.
Advances in scaffolds using muscle tissue engineering are reviewed herein.
Surface microstructure is a critical parameter for scaffolds used in skeletal muscle tissue engineering.
Finally, the options for future developments in the field of skeletal muscle tissue engineering are presented.
Electrically conducting scaffolds have attracted tremendous attention in skeletal muscle tissue engineering.
This chapter summarizes the use of conductive biomaterials in research for skeletal muscle tissue engineering.
Alignment of myocytes or myotubes is critical for skeletal muscle tissue engineering.
The development of a suitable scaffold for muscle tissue engineering in vivo remains a major obstacle.
We therefore conclude that the current protocol is not recommended for skeletal muscle tissue engineering purposes.
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