Sentence examples for muscle target from inspiring English sources

We find that joint inactivation of β- and γ-catenin scrambles motor neuron settling position in the spinal cord but fails to erode the predictive link between motor neuron transcriptional identity and muscle target.

This glutamatergic synapse must respond to greater than a 100-fold increase in the size of the muscle target from first to third instar larval stages.

This suggests that factors other than segmental identity dictate their final alary muscle target.

We find that in these embryos, the tip cells remain stably attached to their initial posterior alary muscle target at A5/A6.

The Fz3 −/− experiments reported here provide in vivo evidence for this model, and suggest that the hypothesized survival factor(s) reside distal to the plexus but proximal to the developing muscle target.

The final tip cell/alary muscle target is highly reproducible, suggesting recognition through segmental identity, the A3/A4 target being the first encountered by the tip cell that expresses Ubx (LaBeau et al., 2009).

In the spinal cord, the organization of motor neurons into discrete clusters is linked to the location of their muscle targets, establishing a topographic map of punctate design.

Tip cells clearly adhere to their final alary muscle targets, but our movies also show distortion of transient muscle targets as the tubules move forward, suggesting substantial adhesion between tip cells and the more posterior alary muscles (Movie S2).

Nevertheless, many axons seem to stall along the axonal path, leaving a reduced number to reach their muscle targets.

Clinical experience and optimal muscle targeting is important in improving the safety and tolerability profile in onabotulinumtoxinA treatment 26.

Consistent with this view, when all the normal muscle targets are ablated, tip cells can make stable contacts with the A2/A3 alary muscle.