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In WT myofibers, mitochondria were abundant between adjacent nuclei at the muscle surface muscle (Fig. 3A) and in a repeated sarcomeric pattern within muscles (Fig. 3A′).
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Figure 3 Illustration of the pectoralis major muscle including the muscle surface patch and a limited number of muscle fibres.
Taller people have a faster metabolism as well, simply because they have more muscle surface area.
We could detect some Laminin (Lam) staining at the muscle surface, like in mammalian muscle cells, and could detect Lam immunoreactivity at the NMJ (Fig. 2A).
In Drosophila, as in vertebrates, NMJs are embedded in the muscle surface, surrounded by complex infolded muscle membranes rich in postsynaptic cytomatrix and neurotransmitter receptors.
Factors like area of the detection surface, shape of electrode, distance between electrode detection surface, location of electrode with respect to the motor points in the muscle, location of the muscle electrode on the muscle surface with respect to the lateral edge of the muscle, orientation of the detection surfaces with respect to the muscle fibers mainly have an effect on EMG signal.
Overall, the data presented above establish a new paradigm for skeletal muscle tissue engineering, by showing that it is possible and relatively simple to create an artificial muscle by exploiting a contracting muscle surface as an 'anatomical bioreactor'.
Moreover, ES is a surface muscle.
The highest uptake was predominantly within muscles, a few centimetres from the muscle surface.
The electrodes were inserted into the masseter muscles and sutured at the muscle surfaces to prevent them from dislodging. Figure 1 shows a schematic configuration of the EMG measurement setup.
Surface electromyography (EMG) was recorded from wrist extensor and flexor muscles using surface electrodes placed over the muscle bellies 3 cm apart.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com