"The factors get taken up by the fibroblasts and the non-muscle population of cells and they initiate a genome-wide switch of the programme of the cells so that it now begins to activate thousands of muscle-specific genes and it turns off thousands of fibroblast genes".
In adult skeletal muscles, a population of muscle stem cells, also called satellite cells, is located on the surface of myofibers in close contact with the myofiber plasma membrane and beneath the basal lamina, and this well-defined anatomic localization represents their niche [176] (Fig. 5C).
Similarly, the localization of αSMA, a marker of the smooth muscle population surrounding the ureter, was also unaltered (Figure S7G L).
We have shown that subtle developmental defects in the expression of MyoD and later the size of muscle populations derived from the fourth pharyngeal arch can lead to later susceptibility to OM.
(ii) In human muscles a population of myoendothelial cells that co-express myogenic and endothelial cell markers (CD56, CD34, CD144) have been described to extensively contribute to regeneration upon transplantation into cardiotoxin injured skeletal muscle of SCID mice 87.
Vertebrate skeletal muscle contains a population of mononuclear cells, termed satellite cells, which reside underneath the basal lamina of myofibers and function as stem cells in growing and regenerating postnatal muscles.
Although adult skeletal muscle includes a population of progenitor stem cells that can generate cells of the myogenic lineage and cells with neurogenic properties, 34 it remains to be determined whether stem cells can induce the functional reinnervation of regenerated muscles.
In fact, though the capacity of muscle to regenerate relies primarily on a specific population of muscle stem cells, named satellite cells, the inflammatory cells that infiltrate the injured muscle appear to be as critical for successful regeneration.
Very often, the evaluation of the coactivation of the PFM and their synergists is presented in the context of the proper functional mechanism of these muscles in the population of healthy subjects.
In this manuscript, we found FGFR1 to be synthesized in a population of muscle fibers within atrophying muscle which appeared to be resistant to reduced load.
Skeletal muscle has a tremendous ability to regenerate, attributed to a well-defined population of muscle stem cells called satellite cells.
