Sentence examples for muscle of type from inspiring English sources

For example, this methodology was applied to investigate the effects of intensive insulin treatment for 10 days on the mRNA profile in skeletal muscle of type 2 diabetic patients [8].

Following reports of aberrant p38 MAPK signalling in skeletal muscle of type 2 diabetic patients [10] and increased phosphorylation and activity of p38 MAPK upon hyperglycaemia in cultured L6 myotubes [46] we decided to asses whether insulin action upon mitogenic signalling pathway can be also implicated in the pathogenesis of type 2 diabetes in LBW men.

The mechanisms by which TZDs exert their insulin sensitizing action in skeletal muscle of type 2 diabetic patients are not yet fully understood, but may include increased downstream insulin receptor signaling [10], [11] and enhanced fatty acid uptake and oxidation [12], [13].

On the basis of these observations, we propose that increased mitochondrial fusion caused by PGC-1β-induced Mfn2 contributes to a fully optimal mitochondrial activity in muscle and liver tissues, which may be defective in skeletal muscle of type 2 diabetic patients.

Specifically, pink1 transcription was suppressed in the skeletal muscle of type 2 diabetic patients.

This revealed a gradual fall in ATP turnover rate in muscle of type 2 diabetic subjects during the isoglycemia study.

The chapter also explains uptake into skeletal muscle of type-1 and type-2 diabetic rat models.

Increased uncoupling protein-2 (UCP-2) expression has been associated with impaired insulin secretion, whereas UCP-3 protein levels are decreased in the skeleton muscle of type-2 diabetic subjects.

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In addition, the DX + n-3 group showed a significant muscle atrophy of type 1 and 2A muscle fibers compared to the CT (24.66% and 20.53%, resp).

However, the administration of the hormone significantly increased the slow and fast isoforms of TnT in the GAS muscle of wild type and ob/ob mice (Figure 6B).