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The decrease in FFM primarily occurs as a result of losses in muscle mass, component of FFM, and is considered the most constant marker of aging.
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Voluntary maximal force production per unit of muscle mass (muscle quality) has been used to describe the relative contribution of muscle-mass components to the changes in strength throughout the aging process.
In addition to SFA and VFA, the degree of muscle mass, a major component of body composition, was analyzed.
Muscle mass, a major component of lean body mass (LBM), is important for insulin-stimulated plasma glucose uptake and has an independent association with insulin sensitivity (1, 2).
Muscle mass is a component of function and improvements in the cross sectional area of a muscle have been shown to be associated with the increased strength and force in health [ 12] and disease [ 13].
For this frailty component, muscle mass was not an important performance predictor.
Since low muscle mass is a required component of sarcopenia, and current guidelines do not include low muscle strength alone as evidence of pre-sarcopenia, 27 participants with low strength but high mass were included in the non-sarcopenia group.
Another consequence of the course of RA disease is change in body composition, with reduced fat free mass (FFM), of which muscle mass is the largest component [ 13, 14].
In young children, resting energy expenditure is relatively high while muscle mass and other body components are growing.
We assessed the impact of sarcopenia on impairment in both aspects of functionality and the relative contribution of its components, muscle mass and strength.
Addition of each component increased muscle mass stepwise.
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