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Upon injection, this neurotoxin can effectively reduce the local muscle intensity that can last up to 3 to 6 months before forming a new muscular reinnervation and return to its full function, without significant side effects[8].
To create FRAP curves, the fluorescence intensities were background-subtracted (region chosen in an area devoid of any myofibers), scan-corrected through dividing by the whole muscle intensity, and normalized to pre-bleach values [22].
Almenar et al. [ 29] defined relative signal intensity as the ratio of myocardial signal intensity to skeletal muscle intensity.
Yet, we note that inhibition by epithelial FGF9 is more efficient and a lower production rate is sufficient in the epithelium to achieve the same smooth muscle intensity.
Much as in the experiments, we observe that smooth muscle intensity is similar in treated and untreated WT, but it is reduced in the FGF10-treated receptor mutant.
In our model, smooth muscle intensity is reduced by 61% (Fig. 6C), which lies in the range of the experimental data (40%and90%0% in the right and left secondary bronchi respectively).
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However, significantly different detraining adaptations in peak and mean muscle power were shown between low-intensity and high-intensity muscle strength training groups for inactive older men [ 13].
Pain intensity, muscle strength and kinematic changes were also measured during the step down test after four weeks of intervention.
Four underlying components of physical activity were distinguished based on literature and expert consultation, including intensity, muscle strength, mechanical strain and turning action components.
After 4 weeks, the intervention was performed to assess the functional capacity, pain intensity, muscle strength and kinematics of the trunk and lower limbs.
Another trial [ 12] reported no influence of different muscle strength training intensities (light, moderate and high) on detraining-induced changes in muscle strength in healthy older adults.
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