Sentence examples for muscle hypertrophy when from inspiring English sources

In sheep, this region has been implicated as the locus responsible for the callipyge ("beautiful buttocks") mutation that causes skeletal muscle hypertrophy when a single mutant allele of paternal origin is present [74].

The function of PEG11 in normal fetal skeletal muscle is unclear as is its precise role, if any, in generating muscle hypertrophy when it is over-expressed in callipyge skeletal muscle.

Insulin-like growth factor-I (IGF-I) plays a crucial role in muscle regeneration, can reduce age-related loss of muscle function, and cause muscle hypertrophy when over-expressed [ 1- 5].

We showed previously that myostatin is capable of binding the two activin type II receptors, ACVR2 and ACVR2B (20), and that a soluble form of ACVR2B in which the extracellular domain of the receptor is fused to an Fc domain can cause significant muscle hypertrophy when given systemically to wt mice (24).

In healthy men, it is suggested that a training intensity of 75-80% of 1 RM (6-12 RM sets) combined with multiple sets in each exercise (starting from 1-2 and progressing to 3-6 sets per exercise), give optimal stimuli for muscle hypertrophy when performed 2-3 times per week [ 57].

Genetic studies in numerous species have shown that loss of myostatin results in dramatic increases in muscle mass (2– 7), and pharmacological agents capable of blocking myostatin signaling have been shown to cause significant muscle hypertrophy when given systemically to mice (8).

34 Muscle hypertrophy occurs when muscle protein synthesis outweighs protein breakdown.

Muscles grow (hypertrophy) when protein synthesis exceeds protein degradation.

Another analysis of gene expression in the longissimus dorsi of callipyge sheep examined neonatal animals (less than 5 days of age) and 80 days when muscle hypertrophy has been well established [48].

Muscle samples were collected from 12- and 8-week-old lambs, when muscle hypertrophy is well established in animals with the callipyge phenotype.

Furthermore, increasing dietary protein can help maintain SkM mass during periods of disuse (reviewed in Wall & van Loon, 2013) and induce greater increases in skeletal muscle hypertrophy following chronic supplementation when combined with exercise (resistance) vs. exercise alone (meta-analysis Cermak et al., 2012).