The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation.
Brinkmeier, H. TRP channels in skeletal muscle: gene expression, function and implications for disease.
Alterations in skeletal muscle gene expression of ob/ob mice by mRNA differential display.
Voluntary running, skeletal muscle gene expression, and signaling inversely regulated by orchidectomy and testosterone replacement.
Liu, N. et al. MicroRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart.
We next investigated the relationship between the timing of BET inhibition and the relative impact on the activation of muscle gene expression.
Di Padova, M., Caretti, G., Zhao, P., Hoffman, E. P. & Sartorelli, V. MyoD acetylation influences temporal patterns of skeletal muscle gene expression.
We are now mapping QTL for the various phenotypes and comparing these with skeletal muscle gene expression.
Since irreversible cell cycle withdrawal typically precedes the activation of muscle gene expression during skeletal myogenesis39, the G1 arrest during BETi-mediated inhibition of myogenic differentiation in DM appears paradoxical.
Besides transcriptional mechanisms that control muscle differentiation, postnatal growth and remodeling, there are numerous epigenetic mechanisms of regulation that modulate muscle gene expression.
Myoblast transcriptome analyses indicated that selective disruption of the LBR- or lamin-A-dependent heterochromatin tethers have opposite effects on muscle gene expression, either increasing or decreasing, respectively.
