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An important role for MVI in striated muscle functioning was suggested in a report showing that a point mutation (H236R) within the MVI gene was associated with cardiomyopathy (Mohiddin et al., J Med Genet 41 309 314, 2004).
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Functional analysis of hind limb muscle function was undertaken at 70 days.
Aging-related decline in skeletal muscle function was milder in Agtr1a −/− mice.
However, significant improvement in limb muscle function was not demonstrated (Supplementary Figure 7b).
Our analysis revealed that aging-related decline in skeletal muscle function was remarkably milder in Agtr1a−/− mice (Supplementary Fig. 3).
His potassium, a blood chemical central to muscle function, was extremely low.
Since aging-related decline in skeletal muscle function was retarded in Atgr1a−/− mice, we examined the role of AT1 receptor in muscle regeneration after injury.
In conclusion, a minor advantage of protein supplementation over carbohydrate supplementation during resistance training on mechanical muscle function was found.
The augmented muscle function was measured not only locally in the triceps, but also at the whole body level with the grid hanging test, suggesting that tamoxifen-mediated enhancement of ECC took place in the whole musculature.
Recovery of denervated muscle function was achieved, and simultaneously, the donor muscle, which was innervated by the axotomized TB also recovered at 20 weeks after surgery.
Muscle function was evaluated by measuring maximal twitch tensions in the flexor digitorum superficialis.
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