This review focuses on the nonpathologic aging process in the lung, including structural changes, changes in muscle function, and pulmonary immunologic function, with special consideration of obstructive lung disease in the elderly.
Clearly, this intervention improves respiratory muscle function, which might reduce postoperative pulmonary morbidity.
These guidelines provides assistance for applying physical therapy intervention (diagnosis and treatment) in COPD patients coping with impairments in mucus clearance, pulmonary function, muscle function and exercise capacity, and with limited physical activities due to dyspnoea or exercise intolerance.
48 Coughing ability is a useful parameter for respiratory muscle function; reduced cough efficiency contributes to pulmonary morbidity and should be improved with mechanical cough assistance.
His main research topics are Pulmonary Rehabilitation, Chronic Obstructive pulmonary Disease, Skeletal and Respiratory muscle function, Exercise Training Physical activity, Patient Reported Outcomes in COPD.
Secondary endpoints include: patient-reported outcomes (PROs) (e.g., quality of life, fatigue, depression, etc.) and organ components of the oxygen cascade (i.e., pulmonary function, cardiac function, skeletal muscle function).
and organ components of the oxygen cascade (i.e., pulmonary function, cardiac function, skeletal muscle function).
All these mechanisms contribute to the amelioration of pulmonary, right ventricular and skeletal muscle function and the increase of arterial compliance [ 117].
In addition, high levels of serum or sputum IL-6 have been associated with impaired lung function, pulmonary infections, exacerbations, and skeletal muscle weakness in COPD patients [ 70- 74].
We have recently shown that levosimendan also improves respiratory muscle function in healthy subjects and patients with chronic obstructive pulmonary disease (COPD) [ 18, 19].
