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Therefore, younger patients with better muscle function have more muscle mass with a higher production of cytokines.

Results from the case-control and RCT study on individual pain perception and muscle function have previously been published.

Methods for measuring trunk muscle function have previously been established for younger adults [ 11, 12], but very little is known about these methods in the older adult population.

From the proteomics data, we found that proteins important in muscle function have several AGE modifications that are reduced on RIF treatment.

Many studies that investigated the effect of nutritional supplementation on muscle function have failed to find positive effect on muscle function (Nosaka et al. 2006; Bryer and Goldfarb 2006; O'Fallon et al. 2012).

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The increased production of free radicals and oxidative stress in the context of physical exercise, sport performance, and muscle function has largely been explored [1, 3, 5, 9, 10].

Impaired skeletal muscle function has been reported in patients with chronic obstructive disease (COPD), but such impairment is not homogenous and its distribution between the upper and the lower limbs is still unclear.

Cementless THR with a subtrochanteric femoral shortening osteotomy, rather than a proximal shortening osteotomy with distal advancement of the great trochanter to restore abductor muscle function, has been described as it avoids the risk of fibrous non-union of the great trochanter [7].

A tumour-related, muscle mass-independent decrease in muscle function has not been described before.

Whether 1,25 vitamin D is also effective to improve muscle function has been insufficiently investigated.

Traditionally, the main means of assessing muscle function has almost exclusively been through volitional testing [ 11].

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