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Purine nucleotide metabolism is distinctly different between the skeletal muscle fibres types with a tendency for greater ATP degradation and subsequent purine loss in type II relative to type I fibres in response to intense exercise (Jansson et al. 1987; Karatzaferi et al. 2001).
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Manipulation of volume and intensity of resistance training will cause more or less hypertrophy to those respective muscle fibre types.
However, soleus and diaphragm both consist of slow and fast muscle fibre types, and so we compared soleus with the EDL, which is almost exclusively composed of fast muscle fibre types [23].
In addition, the EDL is mainly composed of fast type IIx and IIb fibre types, while soleus comprises slow type I and fast type IIa fibres [23], [24], allowing assessment of the major extrafusal muscle fibre types in mouse.
Common gene expression profiles in skeletal muscle between R6/2 mice, HdhQ150/Q150 mice and HD patients have previously been reported to reflect disease progression and be consistent with the beginnings of a transition from fast-twitch to slow twitch muscle fibre types [34].
For both muscle fibre types, the number of capillaries did not change during CCH.
We also provide a comprehensive description of USP family member expression between muscle fibre types and with changing nutritional status.
The uneven density distribution of dihydropyridine receptors indicates a difference in E-C coupling machinery between muscle fibre types.
The histological staining for oxidative capacity indicated that there was greater diversity of muscle fibre types in the postnatal samples.
Fish myotomes are composed of anatomically segregated muscle fibre types each with distinct contractile and metabolic phenotypes [ 1].
Handling of biopsies and their detailed analysis with respect to muscle fibre types, muscle fibre area, muscle pathology and SC frequency have been reported previously (Eriksson et al. 2005; Kadi et al. 1999a; 1999b; Lindstrom and Thornell 2009).
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