Sentence examples for muscle fiber damage from inspiring English sources

The phenomenon of progressive muscle fiber damage in the limbs was further underscored by caspase-3 staining.

A farnesyltransferase inhibitor reduced these nuclear abnormalities and significantly prevented embryonic senescence and muscle fiber damage induced by zProgerin.

However, the abolishment of the inhibitory effect exerted by TNF on muscle regeneration after injury constitutes a tempting approach for the therapy of diseases involving muscle fiber damage [53], [54].

Possibly, in response to muscle fiber damage, STAT3 is phosphorylated in damaged myofibers acting as a localized chemotactic stimuli for the SC and inflammatory cell populations to migrate toward.

It was believed that exercise may cause muscle fiber damage and inflammation in JDM [ 24].

But excessive physical muscle activity is critical for DMD patients and results in muscle fiber damage.

The satellite cells will then still be available for repair of muscle fibers damaged by membrane fragility-induced events.

Because studies have shown that dysferlin is likely involved in Ca2+-dependent membrane repair of damaged skeletal muscle fibers (19, 28, 29), we reasoned that potential detrimental effects of myostatin inhibition in terms of increasing muscle fiber stress and damage might be more pronounced in Dysf −/− mice.

In DCM, the heart muscle fibers are damaged, causing the weakness and reduction of thickness of walls of heart chambers.

If the patients had been experiencing muscle soreness and contractile fiber damage from IMST, one would have expected diminished muscle performance, rather than increasing performance.

Our results demonstrate that inhibition of Il6 activities is beneficial to dystrophic muscle decreasing inflammation-induced myonecrosis, favoring the maintenance of muscle function, and preventing exercise-induced fiber damage and loss of muscle strength.