Sentence examples for muscle differentiation phenotypes from inspiring English sources

Muscle differentiation phenotypes were assessed as (1) the ability of single nucleated cells to elongate and (2) the efficiency of cells to fuse and form syncytia containing three or more nuclei (Straube and Merdes, 2007).

The prdm1a mutant phenotype, early and increased fast muscle differentiation, is the opposite of the Pbx-null phenotype, delayed and reduced fast muscle differentiation.

We demonstrate that it is an inhibitor of Mef2 activity and muscle differentiation, and on the basis of this phenotype, we call it Holes in muscle (Him).

Recently, it was proposed that activation of the rest/nrsf target genes overrides muscle differentiation pathways and converted myoblasts to a physiologically active neuronal phenotype [ 102].

MiR-145 has previously been demonstrated to promote smooth muscle differentiation by targeting multiple factors involved in the regulation of smooth muscle phenotype including Krüppel-like factors,, myocardin and angiotensin converting enzyme.

Puri, P. L. et al. Differential roles of p300 and PCAF acetyltransferases in muscle differentiation.

The improvement in the stabilization of muscle phenotype in anti-Il6r treated mdx mice was monitored analyzing relevant markers of muscle differentiation and maturation.

For instance, the alternative splicing of muscle-specific genes is abnormally regulated in mice overexpressing FRG1 and showing an FSHD phenotype [ 21], and so inappropriate regulation of FRG1 during the early phases of muscle differentiation may have serious effects on the formation of muscle fiber.

To better define the improvement in the stabilization of muscle phenotype and muscle growth in anti-Il6r treated mice, we analyzed other relevant markers of muscle differentiation.

Strikingly, expression of mouse Mef2c rescued the cited3 morphant phenotype (Fig. 7) suggesting that mef2c is the main transcriptional target of Cited3 in skeletal muscle differentiation.

The cell substratum modulates skeletal muscle differentiation.