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Myoglobin, which is needed for muscle development, is also protein.
Mid-arm muscle development is enhanced with greater levels of physical activity.
Understanding muscle development is crucial for generating novel regenerative therapies for muscle diseases and treating muscle injuries.
Myostatin, a negative transcriptional regulator of muscle development is absent from the Always Correlated landscape and poorly correlated to the fast (0.33) and slow (0.26) twitch modules.
The transcriptional dysregulation of genes involved in heart and muscle development is consistent with previous data suggesting that some of the heart teratogenesis may be expression-driven [24], [25].
Important roles of Dlk1 in muscle development is also evident by the observations that Dlk1-null mice show distinct phenotypes including increased mortality during late gestation and early neonatal development, skeletal malformations, and decreased growth rates accompanied by increased adiposity [26].
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Several pathways related to muscle development were enriched with predicted targets for the differentially expressed miRNAs.
Cardiac myoblasts isolated from canine embryonic hearts characterized by expression of myocardin A, a promyogenic transcription factor for cardiovascular muscle development were pretreated with Epo and then exposed to TNF-α.
Greater leg muscle development was found in males of the Parc Cwm cromlech, possibly the result of hunting or herding, confirming the sexual dimorphism found in previous analyses of the remains.
Also, some principles of muscle development are similar [3], [4].
Changes in the position and morphology of individual muscle cells were analyzed in vivo in wild type embryos undergoing tail extension and in embryos in which muscle development was perturbed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com