However, percent change in muscle oxygen consumption was negatively correlated with baseline (r = - 0.679, p = 0.001).
However, muscle oxygen consumption improved in patients with low baseline and deteriorated in patients with preserved baseline.
Its slope, expressed in % units per minute (downslope, %/minute), has been shown to be a proxy for local muscle O2 consumption rate [28].
In the vastus lateralis, average muscle O2 consumption rate was 61 ± 9%/minute during the HF protocol versus 69 ± 23%/minute during the MF protocol (P = 0.5).
In the present study we observed an increase of the local muscle O2 consumption rate of similar degree in both NMES protocols, and also in both patient groups.
These data establish KATP channel-dependent musclin production as a potential mechanistic link coupling "local" skeletal muscle energy consumption with mobilization of bodily resources from fat.
Figure 2 Change scores in thenar muscle oxygen consumption rate (tissue oxygen saturation (StO 2 ) downslope) as measured by near-infrared spectroscopy (NIRS) during a vascular occlusion test for each neuromuscular electrical stimulation (NMES) protocol and patient group combination.
To investigate the changes in muscle oxygen consumption (m˙VO2) using near-infrared spectroscopy (NIRS) after 4 weeks of training with functional electrical stimulation (FES) cycling in nonambulatory people with multiple sclerosis (MS).
Interestingly, RBC transfusion-induced changes in NIRVO2, in the recovery upslope of the reperfusion phase, in PPV, and in MFI were all in the same direction, suggesting that an improvement or worsening in microvascular reactivity, microvascular perfusion, and microvascular blood flow may be associated with an increase or decrease in local muscle oxygen consumption, respectively.
Heart has also an impressive reserve capacity; human cardiac muscle oxygen consumption can rise four-fold without any effect on the steady-state ATP levels.
