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Levels of Fgf10, Shh and Ptc expression, as well as levels of smooth muscle concentration, decrease progressively, and proportionally to the FGF10 production rate (supplementary material Fig. S6).
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In the presence of this irrelevant scFv, the 50 % decrease in muscle concentration was always delayed by less than 10 min, which was considered as non-significant (Figs. 2 and 3).
Variability in muscle concentrations between fish species decreased when concentrations were normalized to lipid content.
Hence, it is possible that muscle concentrations could be similarly decreased in humans.
Muscle concentrations of free His, Leu, and Val decreased and Gly and β-alanine tended to be increased by HDD compared with HAD.
This latter was estimated assuming that, in transition from rest to exhaustion, its concentration decreases by 18.55 m-mole · kg−1 muscle wet weight (in a maximally working muscle mass equal to 30% of the overall body mass).
Muscle interstitial glycerol concentrations decreased by 7±6%6%, 13 ± 9% and 27 ± 9% during the subsequent hyperinsulinaemic steps in type 2 diabetic men, while this decrease was more pronounced in men with NGT (21 ± 7%, 38 ± 8% and 53 ± 8%; ANOVA time × group p = 0.014, Fig. 2d; ESM Table 1).
As the VEGF concentration decreases (inside the matrigel, or in the ECM surrounding the muscle fibres) the proliferation stimulus diminishes, permitting these hematopoietic/endothelial precursors cells to then differentiate into muscle fibres.
Mutant Ryr1 muscle showed decreased concentrations of Ca2+ and K+ in the myoplasm and an increased permeability for K+ in muscles at rest.
Since the original observation by Randle, it has been established that increased fatty acid concentrations in the muscle decrease glucose metabolism (reviewed in [ 4]).
Thereafter, concentrations decreased gradually.
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