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Furthermore, they display a wide spectrum of muscle cell developmental stages [ 96].
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To analyze muscle cell development in a perturbed developmental context we misexpressed the Xenopus homeodomain-containing transcription factor Bix1 [21] in muscle precursors, using the sna>Bix construct, which had previously been shown to cause shortening and/or bending of the tail when electroporated in Ciona embryos [22].
In this work, we reported the transcriptome comparison of broiler and layer breast muscle cells at different developmental stages, and identified many genes and processes that might contribute to muscle hypertrophy and muscle mass control.
To identify the underlining molecular mechanisms of the above phenomena, we used Affymetrix Chicken Genome Array to examine the gene expression profiles of broiler and layer skeletal muscle cells at different developmental stages.
In order to discover the molecular mechanisms determining the divergent muscle growth rates and muscle mass control in different chicken lines, we systematically identified differentially expressed genes between broiler and layer skeletal muscle cells during different developmental stages by microarray hybridization experiment.
In addition to developmental stage specific muscle cell morphology, we observed large multinucleate cells in L4 cell culture, but rarely in cells isolated from younger nematodes (Figure 5E).
These findings resemble a developmental stage between fibroblast and mature smooth muscle cell.
PcG proteins contribute to differentiation through their ability to repress transcription of developmental regulators in committed cells, including skeletal muscle cell lines.
Its pleiotropic functions are still being enumerated and include acting as a Th2 cell developmental determinant, a T/B cell growth factor, an IgE/IgG1 class-switch inducer and a muscle cell contraction inducer.
% skeletal muscle cell.
Epigenetic regulation of smooth muscle cell plasticity.
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