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In chicken pectoral muscle cell cultures, FST enhanced muscle cell development (Link and Nishi 1997).
Genetic Srf deletion studies showed SRF to be indispensable for in vivo skeletal and cardiac muscle cell development.
FST's inhibition of MSTN binding to its receptors has been demonstrated in vitro (Lee and McPherron 2001), supporting that the enhancement of muscle cell development by FST was probably due to FST's suppression of MSTN.
Moreover, muscle cell development in Ciona mirrors many aspects of muscle cell gene regulation and morphogenesis documented in other organisms, and as such may serve as a paradigm for related studies of in vivo cellular behaviors.
To analyze muscle cell development in a perturbed developmental context we misexpressed the Xenopus homeodomain-containing transcription factor Bix1 [21] in muscle precursors, using the sna>Bix construct, which had previously been shown to cause shortening and/or bending of the tail when electroporated in Ciona embryos [22].
Up-regulated genes are involved mainly in muscle cell development (10 of 41 BP terms).
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This was accompanied by the changes in many myofibril-specific and other striated muscle cell development-associated genes among the unique regulated genes for the stages [ 33].
RING finger protein 13 (RNF13) is a newly identified E3 ligase reported to be functionally significant in the regulation of cancer development, muscle cell growth, and neuronal development.
Because the growth rate of skeletal muscle cells vary a lot during development between broilers and layers, we wanted to identify genes with expression traits significantly correlated with chicken muscle cell growth rate, these genes might directly or indirectly involve in muscle cell growth control.
Zebrafish embryos lacking Ntla form floor plate (fp) at the expense of notochord, which results in a difference in muscle segment shape and a lack of muscle pioneer cell development (Halpern et al., 1993).
(E ) Schematic representation showing coronary artery (CA) smooth muscle cell (red) development coincident with aortic attachment and initiation of blood flow at the coronary artery remodeling zone (CA rz).
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muscle cell proliferation
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muscle cell function
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muscle cell biologist
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muscle cell layer
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muscle arm development
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