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In a rat cecal ligation and perforation sepsis model, plasma NOx- level (NO chemiluminescence) was maintained at baseline by NO inhibition (L-NIL) and skeletal muscle capillary geometry, hemodynamics and RBC O2 saturation (SO2) were quantified (spectrophotometric functional imaging).
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Muscle capillary basement membrane width and its relationship to diabetes mellitus in monozygotic twins.
In AW compared with YW, muscle capillary contacts were lower overall (YW: 2.36 + 0.32 capillaries; AW: 2.08 + 0.17 capillaries), specifically in type II (YW: 2.37 + 0.39 capillaries; AW: 1.91 + 0.36 capillaries) but not type I fibers (YW: 2.36 + 0.34 capillaries; AW: 2.26 + 0.24 capillaries).
Relationship between leg muscle capillary density and peak hyperemic blood flow with endurance capacity in peripheral artery disease.
In exercise, the maximal oxygen consumption is proportional to muscle capillary density.
The aim of this study was to determine if skeletal muscle capillary density is lower in patients with peripheral artery disease (PAD) and if capillary density relates to functional limitations.
We hypothesized that skeletal muscle capillary density is lower in PAD and is related to the functional impairment observed in this population.
Capillary PO2 is determined by arterial oxygen content, blood flow rate, capillary geometry, and oxygen consumption.
Ohm's law and the capillary geometry were used to calculate conductivity, Figure 1 and Table S1 in the Supporting Information.
We have used a spectrophotometric functional microvascular imaging system to quantify capillary geometry, red blood cell flow and red blood cell hemoglobin oxygen saturation during sepsis.
Simionescu, N., Simionescu, M. & Palade, G. E. Permeability of muscle capillaries to exogenous myoglobin.
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