Exact(1)
Multiple mechanisms have been suggested based on animal studies including reduced skeletal muscle capillary formation, muscle fiber isoform switching, reduced glycogen synthase activity, and impaired insulin-induced glucose transporter 4 (GLUT4) plasma membrane translocation [18] [21].
Similar(59)
The patterned patch exhibited enhanced cardiac functions, reduced cardiac hypertrophy and fibrosis, increased migration from patch to the infarct area, neo-muscle and capillary formation along with improvements in cardiac functions.
Muscle capillary basement membrane width and its relationship to diabetes mellitus in monozygotic twins.
In AW compared with YW, muscle capillary contacts were lower overall (YW: 2.36 + 0.32 capillaries; AW: 2.08 + 0.17 capillaries), specifically in type II (YW: 2.37 + 0.39 capillaries; AW: 1.91 + 0.36 capillaries) but not type I fibers (YW: 2.36 + 0.34 capillaries; AW: 2.26 + 0.24 capillaries).
In exercise, the maximal oxygen consumption is proportional to muscle capillary density.
Relationship between leg muscle capillary density and peak hyperemic blood flow with endurance capacity in peripheral artery disease.
The aim of this study was to determine if skeletal muscle capillary density is lower in patients with peripheral artery disease (PAD) and if capillary density relates to functional limitations.
Here we show that gene transfer of Ad.ecSOD, but not Ad.ecSOD-ΔHBD, increases H2O2 production in adductor muscles, as measured by Amplex Red assay, which predominantly detects extracellular H2O2, as well as promotes blood flow recovery and capillary formation in response to hindlimb ischemia.
Mannose potently reversed the 2-DG induced HUVEC cytotoxicity (Fig. 3D) and capillary formation (Fig. 3E).
Anti-angiogenic therapy is initially active on capillary formation.
They form cell sheets that can improve capillary formation.
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