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For instance, abnormal increase in arterial blood pressure set-point during orthostatic challenge might enhance sympathetic nerve activity to the heart and the skeletal muscle arterioles, causing increased heart rate and total peripheral resistance and bringing the observed blood pressure value to a higher level.
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The resultant angiotensin II octapeptide (previously called hypertensin, or angiotonin) acts via receptors to constrict arterioles, causing a rise in both systolic and diastolic blood pressure.
In hypertension, look for thickening of the arterioles (causing "copper-wire" or "silver-wire" appearance) and arteriovenous nicking (AVN) (constriction of the venule where it crosses a rigid arteriole hardened from long-standing hypertension).
Swelling of endothelial cells and fluffy masses (fibrin) in arterioles caused narrowing and closure of vascular lumens.
During supine rest, CFS patients had increased sympathetic nerve activity to the heart, the skeletal muscle arterioles and the adrenals; the latter causing increased plasma levels of epinephrine.
H2O2 evokes a concentration-dependent biphasic effect in the skeletal muscle arterioles (SMAs) and mesenteric arteries in the rat, causing vasoconstriction at lower concentrations and vasodilation at higher concentrations (Gao et al. 2003, Cseko et al. 2004, Csato et al. 2014), whereas, H2O2 induces only vasodilation in the rat coronaries (Csato et al. 2014).
Hong, K. et al. Mechanical activation of angiotensin II type 1 receptors causes actin remodelling and myogenic responsiveness in skeletal muscle arterioles.
Endothelium-dependent vasodilation in myogenically-active mouse skeletal muscle arterioles: role of EDHF and K+ channels.
Endothelium-dependent vasodilation in myogenically active mouse skeletal muscle arterioles: Role of EDH and K channels.
NO-mediated microvascular responses were compared by assessing acetylcholine-induced dilation in isolated, pressurized first-order skeletal muscle arterioles, as we previously reported [16].
Spinotrapezius muscle arterioles were studied by intravital microscopy.
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