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In concert with these inflammatory changes, the thickness of the airway wall structural components (epithelium, lamina propria, smooth muscle, and adventitia) also increases with disease severity.
The first step towards the study of individual layers was the separation of the mucosa and submucosa layers away from the detrusor smooth muscle and adventitia (See Additional file 1).
In a rabbit model of SAH, Satoh and colleagues showed PARP activation within the smooth muscle and adventitia of blood-exposed vessels and that PARP inhibition decreased the severity of vasospasm [ 108].
In that study, progression of COPD from GOLD stage 0 to 4 was associated with an increase in the volume of the airway wall tissue (due to an increase in epithelium, lamina propia, muscle and adventitia) and the accumulation of inflammatory mucous exudates in the lumen of the small airways.
An analysis of images from sections shows the relative density of ChAT fluorescent fibers in the urothelium, lamina propria (sub-urothelium), detrusor muscle, and adventitia in comparison with areas immunostained by a pan-neuronal marker (PGP9.5), sensory nerves (TRPV1), and substance P containing fibers.
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Tumor cells were observed in mucosa, submucosa, muscles, and adventitia.
Intima and adventitia are normal.
Media and adventitia are normal.
Media and adventitia are normal (2) The medial type is the most frequent (60 70 %) and corresponds to a rarefaction of smooth media muscle cells replaced by fibrosis.
The intima, internal elastic lamina and adventitia are normal.
Nerve bundles were located in the deep vaginal muscularis and adventitia of the posterior vaginal wall.
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