Sentence examples for murine version of from inspiring English sources

ch5D12 is a molecularly engineered human IgG4 antibody containing the variable domains of the heavy and light chains of the murine version of 5D12 (mu5D12).

hu5A8 is a molecularly engineered human IgG4 antibody retaining the binding and functional properties of the murine version of 5A8 (mu5A8).

In the present series of experiments, we evaluated whether delivery of a species-specific (murine) version of GC1 to cones of the postnatal GC1KO mouse could restore function to and preserve these cells.

The murine version of etanercept exhibited an inhibition of arthritis progression when used alone or in combination with F8-IL10.

Cohorts of mice bearing the same tumor line were then treated with 4D5, the murine version of Herceptin, or vehicle.

We show that intracranial injection of an IgG2a murine version of Crenezumab-mC2 failed to clear plaques or induce a pro-inflammatory response.

We performed a direct comparison of AAV8 mediated gene transfer of the murine versions of both genes at three doses (1×1012, 3×1011 and 1×1011 GC/mouse) in chow-fed Ldlr−/−Apobec1−/− mice using a liver specific promoter, thyroxine binding globulin (TBG).

We produced murine versions of the antibodies: Bapineuzumab (3D6), Crenezumab (mC2) and Gantenerumab (chGantenerumab) with an IgG2a constant region.

We produced murine versions of Crenezumab (mC2), Bapineuzumab (3D6) and a mouse/human chimeric version of Gantenerumab (chGantenerumab) all with an IgG2a constant regions.

To study the therapeutic potential of a combination of TNF blockade and F8-IL10, we here report on the cloning, expression and characterization of murine versions of etanercept (murine TNFR-Fc) and of F8-IL10 (F8-muIL10).

CTLA4 shares significant sequence homology between the human and murine versions of the molecule, so that fusion compounds containing this ligand can be effectively studied in murine models of a variety of human diseases.