Sentence examples for murine tuberculosis models from inspiring English sources

The mutant failed to survive in macrophages and in murine tuberculosis models.

The IC31® adjuvant contains a KLK peptide and a TLR-9-triggering non-CpG oligonucleotide (ODN1a) [27], [27] and confers protective efficacy in challenge models of murine tuberculosis [28], [29].

The characteristics of the mutant were examined in an in vitro stationary phase model, in response to stresses; in murine bone marrow derived macrophages and in an acute and an immune resistant model of murine tuberculosis.

Econazole (free or encapsulated) could replace rifampicin and isoniazid during chemotherapy of murine tuberculosis.

The present study was designed to evaluate the chemotherapeutic potential of alginate nanoparticle-encapsulated econazole and antitubercular drugs (ATDs) against murine tuberculosis.

Serum amyloid proteins are induced during tissue injury, infection and inflammation and are detected during murine tuberculosis [54] and in human tuberculosis patients [55].

We hypothesised that a similar population might be present in chronic, murine tuberculosis.

We report here a dehydropeptidase-deficient murine model of tuberculosis (TB) infection that is able to partially uncover the efficacy of marketed broad-spectrum β-lactam antibiotics alone and in combination.

In a murine model of tuberculosis, IL-17 induced IL-17 induced a key factor in neutrophil accumulation and exacerbated lung inflammation by inducing proinflammatory cytokines [ 33].

In a previous study carried out in a murine model of tuberculosis, different M. bovis strains showed wide virulence variability [ 8].

IT aerosol delivery was therefore used to administer BLM in mice to model lung fibrosis [ 19, 34] and, in another context, to deliver siRNAs to modulate lung immunopathology in a murine model of tuberculosis [ 35, 36].