Sentence examples for murine system to from inspiring English sources

To determine the efficacy of pharmacological purging by ATP, we designed a murine system to mimic the conditions expected in the clinical setting of autologous transplantation using simulated partial remission marrow (SPRM) which was prepared by mixing normal marrow cells and L1210 cells at a ratio of 9 1.

We have designed a novel Cre recombinase (Cre -based murine system to overCre -based problemurined thereby enable tracking and isystemon of individual in vivo infectod cells.

Newly proposed differences in genetic pathways that cause cancer in humans and mice invigorated the ongoing discussion about the legitimacy of the murine system to model the human disease.

However Wang and co-authors used studies in murine systems to further address whether knockdown of Wdnm1-like affected DC differentiation, finally claiming "that lnc-DC is vital for DC differentiation in both human and mice".

For instance, the PPE family members (tested in the current panel) have been shown to mature dendritic cells via TLR-2 stimulation (in a murine system) leading to a different quality of antigen-presentation and expansion of antigen-specific immune cells [ 62].

However, neither monocyte to DC differentiation nor maturation of immature DCs was induced in the murine system pointing to a species difference in the effects of CD137 ligand signaling between human and murine monocytes.

Peptides from this antigen are now being examined for their potential to serve as a correlate of protection for C. burnetii vaccine efficacy in the murine system, and to assess the potential for developing an IFN-γ based immunodiagnostic assay, which could provide direction for more accurate human Q fever diagnosis.

An intriguing murine model system to study direct effects of lipid overload in muscle has been established earlier, the muscle creatin kinase (MCK) promoter; medium expressor(m); human(h) LPL-expressing mouse.

The failure of VIP to augment macrophage IL-10 production, unlike the murine system, is likely to result from the lack of activation/phosphorylation of CREB, a transcription factor that is readily activated in the murine system by VIP [ 10].

We have constructed a two-vector based rapalog-inducible system for STAT1 expression and evaluated applicability in stable murine systems according to the above-mentioned requirements.

Unlike its effect in the murine system, VIP failed to modulate human T-cell activity.