The functional differences to the murine system presumably explain the susceptibility of these individuals to mucocutaneous, but not systemic, fungal infections.
Because systematic analyses in the human system are not feasible, we went on analyzing the effects of GM-CSF-activated monocytes on the murine system.
Murine and patient trials are conducted concurrently, and information obtained from the murine system is applied towards future clinical management of the patient's tumor.
The present investigation was carried out to investigate gender dimorphism with respect to the progressive in vivo growth a of T cell lymphoma in a murine system.
The recognition of self MHC class I in the murine system depends largely on Ly49 receptors.
This ODN contained two copies of a CpG motif known to have potent immunostimulatory effects on the murine system [31].
Use of Homo sapiens KLK1 to study physiological effects in a murine system has been previously validated [27].
Rather, in the murine system monocyte subpopulations are classified as CD115+, Ly6Chigh and CD115+, Ly6Clow, respectively, which constitute 50% each [3].
This miRNA was originally cloned in a murine system and therefore there is no data demonstrating that the human homologue can be expressed and processed in HEK293 cells.
We also tested the NNRTIs efavirenz, and a TIBO derivative that was shown to be effective in a murine system [14].
In contrast to the murine system, cyclic AMP elevating agents have been shown to stimulate human DC inducing their activation and migration [4], [5].
