Sentence examples for murine studies we from inspiring English sources
Since much of this knowledge has been advanced from murine studies, we focus our review on how the mouse state has informed the human state, emphasizing the key parallels and differences.
To determine the proportion of immunoglobulin recognizing EDIII DENV-2 type-specific epitopes identified as potently neutralizing in murine studies we used two different EDIII mutant antigens.
In our previous murine studies, we did observe that ex vivo rapamycin resistance does not necessarily confer resistance to rapamycin in vivo [17]; such observations may be due to rapamycin blockade of non-T cell pathways in vivo, such as antigen-presenting-cell populations [39] that may help drive T cell expansion in vivo.
From murine studies, we conclude that dissemination rate is linearly dependent on the diameter of a lesion.
In order to clinically validate our findings from murine studies, we sought to characterize fungal calcineurin-dependent responses in alveolar macrophages from lung transplant recipients.
In keeping with our murine studies, we observed that both NFAT- and NF-κB-dependent signalling pathways contributed to the inflammatory response to AF in human alveolar macrophages (Fig 9B).
In both murine and human studies we found that calcitriol pre-treatment yielded a significant increase in cell death over freezing alone.
This may appear somewhat counter to our murine studies, above, where we showed that ephrin-B1/B2 signaling was necessary for healing, but perhaps suggests that ephrinB1/B2 signaling during wound re-epithelialization needs to be very finely balanced: some is needed for driving sufficient loosening of junctions to enable re-epithelialization, but too much might be detrimental to healing.
In these studies we describe a murine model of opioid-induced hyperalgesia (OIH).
In this review we discuss previous murine studies that explored the CV-GJ relationship in isolated mouse heart preparations with approximately 50% reduced Cx43.
To remove the complexity inherently associated with human studies, we used mature murine primary hippocampal cultures to determine the effects of Aβ specifically on neuronal miRNAs.
