Sentence examples for murine studies using from inspiring English sources
Our subjects were 4 7 weeks of age, prior to the early onset of presbycusis in these mice, which were also used in prior murine studies using GTTR [3], [26], [28], [44].
Murine studies using the twitcher mouse model for Krabbe disease preceded clinical therapies, and showed CNS and peripheral engraftment followed by significant remyelination [ 51].
Similar observations have been made in murine studies using anti-CD20, where marginal zone B cells, B1 cells and germinal centre B cells are more resistant to depletion [ 47- 49].
Murine studies using TNF-receptor knockout mice and TNF transgenic mice point to a primary role in the local proliferation of synovial fibroblasts rather than to tolerance impairment of lymphocytes or death of local joint cells [ 14, 15].
In a recent murine study, using an experimental model of lung metastasis and the FDA-approved antiangiogenic drug sunitinib, Welti et al.
In a murine study using C57BL/6 mice, administration of paclitaxel at ultralow dose modulates MDSCs to differentiate into DCs in a TLR4 independent manner [ 110].
Murine xenotransplantation studies using primary patient samples can be very complex and relatively expensive.
However, our recent results obtained from murine brain distribution studies using direct brain perfusion show that P-gp restricts the accumulation of [H]cortisol in specific brain regions, such as hypothalamus, and does not restrict the access of [H]corticosterone in any brain regions sampled (13).
While initial studies using murine retroviral vectors on murine HSC showed that the concept works, a number of clinical studies in the last decade were not informative because of limitations in transduction efficiency and transgene expression.
Thus, it is important to confirm similar responses in murine phagocytes when considering future in vivo studies using a murine model.
Indeed, our previous studies using murine DCs demonstrate that they have a reduced capacity for the degradation of yeast as compared to murine macrophages [7].
