Also, FVB/N and Balb/c murine strains that are commonly used for constructing gene knockout and transgenic animals, develop approximately four tumors and one tumor per mouse, respectively, upon treatment with AOM [76], [77].
It also has become clear that murine strains, in some cases, represent a stereotypic or incomplete picture of their human disease counterpart.
Current murine strains created using the Cre/loxP system are shown in Table 2. Cre transgenic strains can also be generated with Tet-inducible promoters [ 48].
We also examined the variability of thymidine concentrations in plasma and other normal tissue between different murine strains and whether tumours themselves altered plasma thymidine concentration in their hosts.
Inoue et al. demonstrated that disease models and murine strains used in experimental conditions have to be taken into account to explain reported discrepancies [38].
The conventional approach to investigate genotype phenotype relationships has been the generation of gene targeted murine strains.
Different marijuana strains also have these chemicals.
Yagi et al. showed that ICOS expression varies between numerous murine strains and there is a positive correlation between ICOS expression and IL-4 production across strains [23].
The murine strains (DBA, CBA, Balb/c, etc).
Our hypothesis was that murine strains exhibit different cardiac/genomic responses to specific pathogens.
