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Moreover, several variants with CDR substitutions outperformed the murine prototype.
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In this study, we chose to further examine the contribution of the components of this novel axis in a prototype murine model of necroptosis.
An NMT knockout in C. albicans resulted in avirulence in a murine model, and several prototype inhibitors have been reported.
At the amino acid level, it shares considerable identity with sequences of Moloney murine leukemia virus (MoMLV), a prototype MLV.
(PNG 112 kb) Additional file 2: Virulence of P. aeruginosa RP isolates, and prototype strains in a murine model of chronic airways infection.
6 Cardioviruses are well-known pathogens in rodents and Theiler's murine encephalomyelitis virus (TMEV) is a prototype mouse cardiovirus that can cause a chronic encephalomyelitis with demyelination showing many similarities with MS (reviewed in reference 7).
Previous publications have described a prototype based on an amphotropic murine leukemia virus (MLV), encoding yeast cytosine deaminase (CD) that converts the prodrug 5-fluorocytosine (5-FC) to the potent anticancer drug, 5-fluorouracil (5-FU) in an infected tumor.
In this study, we set out to isolate tissue-directed AAV capsids using murine breast cancer and lung tissue as prototype targets.
However, thus far Arg1 is regarded as the prototype activation marker for AAMs in murine macrophages [7].
The murine L929 fibrosarcoma cell line has been the prototype cellular model system for identifying pathways involved in necroptosis.
We previously developed a strategy to recover prototype reovirus strain T3D from cloned cDNAs transfected into murine L929 fibroblast cells.
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