Sentence examples for murine neuronal cell from inspiring English sources

Importantly, we demonstrated that nanoceria induced chemical- and size-specific changes in the murine neuronal cell transcriptome.

In vitro studies for the cytotoxicity, the uptake of these nanoassemblies and the gene silencing were carried out using these PE-Gold NAs in N2a and NB4 1A3 (murine neuronal) cell lines.

To investigate whether MeCP2 represses MHC class I expression, we transfected the murine neuronal cell line N2A with pCMX plasmids that transiently express either human or murine MeCP2A.

Indeed, MVs were isolated from the cell culture supernatants of two murine neuronal cell lines (Neuro-2a and Neuro-2a PK1 cells).

In order to determine whether neuronal cells can also release plasma membrane-derived MVs and to investigate whether these MVs also contain PrPC associated with lipid rafts components, we isolated MVs from cell culture supernatants of a murine neuronal cell line (Neuro-2a) and from its subclonal line (Neuro-2a PK1) [41].

The present study aimed to characterize fluorescently-labeled SL turnover in a murine neuronal cell line (CATH.a).

Similar findings were found in MVs from cell culture supernatants of murine neuronal cells.

In this study, the association of PrPC with MVs shed by murine neuronal cells was demonstrated.

Here, we demonstrate that PrPC is associated with MVs from plasma of human healthy donors and with MVs shed by murine neuronal cells.

Moreover, in vivo biossay in transgenic mice that overexpress murine PrPC and are highly susceptible to murine prions [50] clearly demonstrated that prion infectivity is associated with PrPSc-harboring MVs shed by prion infected murine neuronal cells.

Furthermore we demonstrated that PrPSc is released from infected murine neuronal cells in association with plasma membrane-derived MVs and that PrPSc-bearing MVs are infectious both in vitro and in vivo.