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From 1950s to 1970s syngeneic murine models were used.
Murine models were used to demonstrate that the CD22 ligand binding domain is critical for normal B-cell survival.
The acute and chronic CIA murine models were used to assess the effect of the MetAP-2 inhibitor PPI-2458 as a potential therapeutic agent.
Murine models were used to investigate particle uptake in conditions representing allergic asthma and COPD as well as in corresponding healthy controls.
Novel murine models were generated that mimic the tumor-associated conversion to cyclin D1b, which uncovered potent transcriptional functions of this isoform in developmental phenotypes.
The murine models were allocated to sedentary cage-life or to moderate intensity training 3 to 5 times per week for 4 weeks.
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Murine models are commonly used to investigate bone healing and test new treatments before human trials.
While murine models are powerful tools to study pregnancy and maternal-fetal immune interactions, in contrast to human placental exosomes, the content of murine placental and pregnancy exosomes remains largely understudied.
Murine models are useful tools to study lymphomagenesis and disease progression, as well as potential treatment in a pre-clinical setting.
Adoptive transfer of these TILs to murine models was shown to lead to regression in lung and liver tumors (Rosenberg et al., 1986).
This point is essential since although murine models are very different from humans due to their own evolutionary specificities, when it comes to shock or its treatment, the persistence of fundamental responses shared by all mammals must be acknowledged.
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murine splenocytes were
murine cDCs were
murine macrophages were
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murine iPSCs were
murine residues were
murine genes were
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murine oncoretroviruses were
murine cells were
murine cardiomyocytes were
murine lungs were
murine BMDMs were
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