Sentence examples for murine models using from inspiring English sources

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In vivo assays in murine models using an IVIS imaging system showed that tumors in control antibody-treated animals had no significant increase in bioluminescence activity after SU11274 administration, while HGF neutralizing antibody-treated tumors had a 4- to 5-fold increase in bioluminescence activity at 3 h p.i. and sustained for 10 h.

Subsequent murine models, using either heat-killed and live bacteria or LPS, showed evidence that both TLR2 and TLR4 play a role [14], [15].

We investigated the accuracy of the method in tomographic estimation of f d in murine models using a 17 mm thick phantom.

In recent years, many studies have reported successful inhibition of viral replication in cultured cells or in murine models using transient transfection of synthetic siRNA or plasmid expressing shRNA.

Research in humans and murine models using infection with S. aureus as phenotypic trait have suggested different positional candidate genes, e.g., SEH1L, TNFAIP8, KLK, and CDON [ 16, 17, 50, 51].

Although this has been shown in murine models using Fas ligand [ 69, 70] as the transgene, TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) is a better candidate because its receptor has more limited distribution, thus reducing opportunities for unwanted side effects.

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There are some limitations imposed by the current murine models used for HCM studies.

Therefore, it is vital that tumour microenvironment be accurately mirrored in murine models used to evaluate drug therapies.

These apparent discrepancies may reflect differences in the murine models used i.e. LDLR−/- (current study) and ApoE−/− mice [24,25].

This review provides an overview of the current murine models used to study lung cancer and the advantages and limitations of each model, as well as a retrospective evaluation of the uses of each model with respect to accuracy in predicting clinical benefit of therapy.

Moreover, the BFD-22 antitumor effects were evaluated in a melanoma murine model using B16F10.

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