Sentence examples for murine models suggest from inspiring English sources
CMV antigen and DNA have been identified in atherosclerotic vessels of the human cardiovascular system [21] [23] and murine models suggest an inflammatory link with CVD progression [19], [20].
Although it has been hypothesized that adaptation of the BSE agent through secondary passage in humans may result in a greater risk of onward transmission due to an increased virulence of the agent for humans, our data presented here in two murine models suggest no significant alterations to transmission efficiency of the agent following human-to-human transmission of vCJD.
Experiments in murine models suggest that antibody nucleosome complexes may play a crucial role in the pathogenesis of glomerulonephritis in systemic lupus erythematosus.
Data from murine models suggest that GITR blockade may be most effective when combined with melanoma vaccination strategies and not as monotherapy [ 65].
Murine models suggest that quantities of intracellular mucin in airway epithelial cells results from the balance between mucin production, clearance and secretion.
Murine models suggest that disseminated cells have high survival in circulation and are efficient at extravasation, Additional file 1: Table S4.
19 Additional data from other murine models suggested that rapamycin selectively inhibits Teff function as compared with Treg function.
Furthermore, preclinical work in murine models suggests that local radiotherapy plus intratumoural syngeneic dendritic cells (DC) injection can improve immunologic tumour eradication [ 34].
Overall, evidence from human studies supports experimental observations from murine models, suggesting that initiation of angiogenesis occurs in the pre-malignant stages of cancer development.
Early studies in SLE murine models suggested that blocking the interaction between CD40 and CD154 reduced nephritis and anti-dsDNA antibodies, leading to improved survival [ 28- 30].
Increased expression of sLepR is associated with lower body weight in murine models, suggesting the important role of sLepR in leptin regulation [ 12].
