Sentence examples for murine models studied from inspiring English sources

As all murine models studied (irrespective of diet) display increased p-CREB expression, aberrant hepatic glucagon sensitization appears to be a common feature of Smn depletion, whether it be mild or severe.

Both clinical trials and murine models, studying adoptive immunotherapy using tumor-specific TILs or TCR transgenic (Tg) T cells have shown that immunotherapy is more effective in a lymphopenic than in a lymphoreplete environment 5, 6.

However, compliment activation did not cause the classical symptoms of preeclampsia (increased blood pressure and proteinuria) in the murine model studied by Girardi and co-workers.

Despite the clarity of the murine models, studies in SLE patients have yielded more mixed results, with only some showing correlations between the presence of anti-NR2 antibody and cognitive impairment.

This is supported in kinetic murine modeling studies which have shown that as the tumor progresses, rise in urine levels of FRα precede sera levels considerably [15].

The human and murine model studies revealed that the outcome in infectious diseases is influenced by TNF-α.

Moreover, a murine model study showed that low-level FQ resistance could be overcome with the use of high dose moxifloxacin [ 5].

Many adjuvants that hold promise for induction of CD8 T-cell responses based on murine model studies fail when evaluated in human clinical trials.

Hwu presented data from murine model studies showing that gp 100-specific T cells transduced with CXCR2 (receptor for CXCL1 and IL-8) have enhanced accumulation in tumors, delay tumor growth and lead to improved survival.

Although clinical examples of clearly established mechanisms of resistance to angiogenesis inhibitors remain limited, findings from cell culture and murine model studies have revealed that activation of alternate or redundant signalling pathways may represent one such mechanism (Mizukami et al, 2005; Huang et al, 2010).

These reports suggest progressive weakness and wasting of skeletal muscle in clinical and murine model studies of X-linked hypophosphatemic rickets; Hyp mice quadriceps muscle weight/body weight and strength/body weight have been measured to be approximately 20 25% smaller than wild type mice [28].