Sentence examples for murine models since from inspiring English sources

However, other reports state that some aspects of leishmaniasis immunopathogenesis cannot be completely represented using murine models since they are not the natural hosts for the parasites.

However, caution is needed in interpreting the results from murine models since neither transgenic VEGF-A mice nor double knockout of the JunB and c-Jun mice wholly replicate human psoriasis.

We used a murine model since it might facilitate molecular studies of remodeling by eventually allowing for the use of transgenic models to elucidate mechanisms.

Importantly, STZ did not appear to have an acute toxic effect on podocytes, at least in the murine model, since 3 days after completion of the five day STZ injection protocol apparent podocyte number and density was completely normal in STZ treated mice.

To show the therapeutic potential of perthiol H2S prodrugs, Xian׳s laboratory also tested the protective effect of these prodrugs against myocardial ischemia/reperfusion (MI/R) injury in a murine model system, since H2S was proven to show such effects.

However, these studies were established using a murine model, and since it was later shown that mice have no S100A12 in their genome [ 20], alternate receptors are implicated [ 25].

This point is essential since although murine models are very different from humans due to their own evolutionary specificities, when it comes to shock or its treatment, the persistence of fundamental responses shared by all mammals must be acknowledged.

Since then, development of murine models of persistent and lethal ehrlichiosis has greatly facilitated understanding of the pathogenesis and mechanisms of host defenses against ehrlichial infections.

These observations have since been reproduced in other murine models of AD [ 182, 183].

Genetically engineered murine models (GEMMs) have been recently used to study many aspects of CNS tumors since they represent a more relevant model than orthotopic brain tumor xenograft models.

Since joining the Ingelsson lab in 2019, she has focused on establishing murine models to study the function of novel regulators of adipose tissue formation.