Sentence examples for murine models revealed from inspiring English sources

Among Wnt antagonists, murine models revealed that Dickkopf and secreted Frizzled-related proteins are upregulated in arthritic synovial tissues and may contribute to decreased osteoblast function [ 14].

Explorations in murine models revealed pro-inflammatory signalling through FPR2/ALX in leucocytes transducing accelerated atherosclerosis, whereas direct effects on SMCs potentially increased plaque stability.

Several murine knockout models revealed that development and differentiation of these cells are controlled by transcription factors; and one of the major regulators is the CCAAT enhancer binding protein (C/EBP) family.

All murine colitis models revealed bacteria in contact with the epithelium.

Studying the role of inflammasomes in murine infection models revealed critical roles for ASC and caspase-1 in the host defense against S. aureus and V. cholerae, whereas NLRP3 was surprisingly dispensable, even though these pathogens selectively trigger NLRP3 in vitro.

In particular, murine models have revealed a large number of SLE susceptibility genes, which are organized in the same three broad pathways: apoptosis and processing of apoptotic debris, toll-like receptor (TLR) signaling and type I IFN pathways, and lymphocyte activation in both SLE patients and SLE-prone mice [ 2, 3].

Using a murine model, immunofluorescence revealed that H4K12ac co-localize with 5mC in the sperm nucleus.

The human and murine model studies revealed that the outcome in infectious diseases is influenced by TNF-α.

Remarkably, specific conditional elimination of these cells in a premature aging murine model has revealed their essential role in the onset of several age-related diseases [ 3].

More recently, vaccination using dendritic cells pulsed with EphA2 peptides in a murine colon cancer model revealed that immunization inhibited the growth of MC38 tumors expressing EphA2, but did not have an effect on BL6 tumors that do not express EphA2 [ 68].

Analysis of the virulence of the Δafoch1 mutant in two murine models of infection revealed no attenuation.