Sentence examples for murine models resulted from inspiring English sources

Allergen challenge in murine models resulted in the secretion of TGF-β, MMPs and activation of pro-fibrotic signaling (e.g. p-Smad); treating animals with TAS2R agonists inhibited all of these features.

Bioluminescent data indicates that expression of miR-34a in these murine models resulted in significant reduction in tumor volume up to 21 days post injection relative to premiR-negative control-treated groups (p < 0.001, Figure 4A-D).

This three-factor model can potentially explain how the known susceptibility alleles and IBD-related triggers in existing murine models result in the development of chronic colitis.

The most indicative evidence was found when T-cell proliferation was blocked in different murine models resulting in reduced development of psoriasis [ 10].

Similarly, prostate-specific loss of PTEN in a murine model resulted in tumors with elevated AKT and mTORC1 activity.

In fact, β2-adrenergic receptor inhibition in a murine model resulted in increased dermal fibroblast function and re-epithelialization during the early stages of wound repair [ 24].

Moreover, a diminution of laminin-a5 in a murine model resulted in a transformation from a small intestinal to a colonic mucosal architecture, suggesting that laminin-α5 has a crucial role in establishing and maintaining the architecture of the small intestine [ 29].

The deletion of Nrf2 in murine models results in structural and functional kidney defects that are associated with increased inflammation and oxidative stress [ 18].