Sentence examples for murine models recapitulate from inspiring English sources

These murine models recapitulate the salient features of human NEB mutation, including severe muscle weakness, impaired force generation and histopathological changes including reduced thin filament length and the presence of nemaline rods and bodies.

On the basis of these findings, we conclude that the murine model recapitulated biologic features of the subset of NSCLC adenocarcinoma patients with poor clinical outcomes.

Herein, we characterized a murine model recapitulating the formation of Mikulicz cells in lungs and identified them as atypical inflammatory monocytes specifically recruited from the bone marrow upon K. rhinoscleromatis infection in a CCR2-independent manner.

Genetic ablation of TBX5 in murine models imposingly recapitulates the human phenotype [ 12].

Rodent animal models recapitulate incipient retinal damage, including vasoregression.

Nonetheless, the resulting trained models recapitulate some important behaviors.

We hypothesized that mast cells mediate pelvic pain directly and examined pain behavior using a murine model that recapitulates key aspects of IC.

Here we examine mechanisms of pelvic pain in an established murine model that recapitulates key aspects of IC, including lamina propria mast cell accumulation and pelvic pain [11], 12, 13.

Due to the difficulty of attaining ample specimens from early stage patients, preliminary study of early stage PC diagnosis through PBMC expression analysis may be first carried out in a spontaneous PC murine model which recapitulates the preneoplastic and early neoplastic processes seen in human PC as a proof of concept [31], [32].

31 Following these advances, in a recent study on a murine model that recapitulates the main clinical signs of HGPS, vivo-morpholino ASOs were able to reverse many of the phenotypical alterations seen in these mice.

However, there are only a few murine models that robustly recapitulate these phenomena, especially after relatively short times (<6 months) of disease development [2], [11], [29], [42].