Sentence examples for murine models in from inspiring English sources
We study both human samples in vitro and autoimmune murine models in vivo.
The importance of intermediate filaments in muscle is further strengthened by murine models in which genetically designed intermediate filament mutations are expressed, leading to progressive skeletal or cardioskeletal myopathy in affected mice.
We examined the fate and function of these DCs following their injection using murine models, in order to better understand their interaction with the host immune system.
The reduced production of TNF-α in the M. tuberculosis H37Rv infected cows is in agreement with the lack of visible pathology and reduced virulence as TNF-α has been implicated in murine models in formation and maintenance of granulomas (e.g. [20]).
In cell cultures in vitro and murine models in vivo, IFNα and IFNβ suppress early stages of dengue viral replication; whereas the type II interferon, IFNγ (produced mainly by activated T and NK cells), limits dengue viral replication at later stages [12] [16].
The method however could be used to collect samples from murine models in other areas of research.
Soloviova, K., Puliaiev, M., Foster, A. & Via, C. S. The parent-into-F1 murine model in the study of lupus-like autoimmunity and CD8 cytotoxic T lymphocyte function.
Efficacy of GRN163L was also tested in s.c. murine model in which SCID mice were s.c. inoculated in the interscapular area with 2.5 × 106 myelomaeloma cells.
By contrast, using a transgenic murine model in which expression of NF-κB in macrophages could be induced or suppressed, Connelly et al.148 demonstrated that activation of NF-κB instills macrophages with an antitumour phenotype and leads to a marked reduction of lung metastasis in a mammary tumour model.
We used a murine model of MFS [fibrillin (Fbn)(C1039G/+)] to generate an MFS murine model in combination with genetic βarr2 deletion (Fbn(C1039G/+)/βarr2.
Therefore, we utilized Hoxb7creEGFP mice to generate a murine model in which Ptc1 is genetically inactivated in the ureteric cell lineage [16], [17] (refer to Methods).
