Sentence examples for murine models has from inspiring English sources

The development of methods to study mast cell biology using cell culture and murine models has proven invaluable in this regard.

Pre-clinical evaluation of this approach in murine models has demonstrated efficient anti-leukemic responses with the expression of immunomodulators, in particular GM-CSF and CD80, in irradiated cell vaccines.

Our previous study carried out in murine models has shown that intranasal, but not intramuscular, boosting with AdAg85A could dramatically further enhance protection in BCG-primed mice [14].

[2], [16] Similar work in other murine models has also been undertaken to study other human TSEs (genetic and iatrogenic CJD [17], and sporadic CJD [2]), and has been used to examine emerging TSEs (atypical BSE [18] and chronic wasting disease in deer and elk [19]).

Previous work on murine models has put forward an alternative model to explain oncogene-induced p53 activation, being its main features that it is independent of DNA damage and that it places Arf as the critical sensor of oncogenic signaling that mediates p53 activation [24], [25].

The overexpression of APP in other genetic expression profiling studies in scrapie murine models has been previously reported [ 24].

Modeling human cancers in animals has yielded important findings, and sophisticated murine models have been established to study tumor development.

Murine models have become particularly attractive with the advent of transgenic animals and genome manipulation techniques, and the availability of gene-targeted antibodies [7, 8].

Multiple murine models have proven useful in studying the natural history of neovessel development in the tissue engineering of vascular grafts.

In vitro and in vivo murine models have demonstrated a number of harmful biological effects of e-liquids and their aerosols.

Murine models have provided valuable insights into the mechanisms associated with the development of Huntington's disease, and they are important tools for the design of new therapeutic approaches.