Sentence examples for murine models given from inspiring English sources

Moreover, our results are supported by observations on murine models, given that mice with mutations resulting in under-expression of the clock gene presented obesity and hyperglycemia [ 32, 33].

Bone marrow transplantation experiments in genetically modified murine models have been a powerful tool to examine whether immune cells contribute to a given pathology in vivo.

Leukemic stem cells (LSCs) are cells that can give rise to leukemia in transplant murine models, and therefore have self-renewal property.

Interruption of these late stages has been shown in murine models to confer protection even if given 1 hour after the initiating stimulus.

To gain more knowledge about differences in serological IgG responses between serovars in humans, studies in murine models and at cellular level may give more insight in this biological mechanism.

Beside the peptides currently evaluated for their efficacy in lupus, other peptides hold promise as they gave interesting results in murine models of lupus.

Our data clearly suggests that the STMΔhfq mutant is an effective oral vaccine candidate in the murine model and can be given both in booster as well as in single dose.

Similarly, conflicting results have been reported utilizing murine models.

In murine models of atherosclerosis, hypercholesterolaemia induces monocytosis, which is dominated by the classical subset and these cells give rise to macrophages within atherosclerotic plaques.

Dosing in murine models for both nal-IRI and free irinotecan employed in this study scales appropriately to the clinical setting where nal-IRI is given at a dose density of 40 mg/m2/week [36].

In the murine model, single-fraction TBI was given, subcutaneous rBPI 21 treatment was initiated 24 hours after TBI, and no stem cells were administered to restore hematopoiesis.