Sentence examples for murine models expressing from inspiring English sources

A significant reduction in β-catenin translocation to the nucleus, which is indicative of impaired Wnt signaling functions, has been detected in transgenic murine models expressing familial AD mutations [ 36].

In previous studies from our laboratory we characterized the immunogenicity of Nef from CRF12_BF and BF variants, evaluating the characteristics of the cellular immune response in primary HIV infected persons [33], and in a murine model expressing the protein from DNA and MVA vectors [24].

P McLaughlin (Groningen, the Netherlands) investigated the consequences of targeting monoclonal antibodies to normal and tumour tissue in a transgenic murine model expressing human EpCAM.

The SMA murine model expresses the genomic human SMN2 gene and the human SMNΔ7 cDNA.

Our observation that only aggressive and bone metastatic mammary carcinoma cell lines of our murine model express this receptor is consistent with these studies.

The T70I sod1 zebrafish model offers the advantage over current murine models of expressing the mutant Sod1 protein at a physiological level, as occurs in humans with ALS.

In the present study, we intended to utilize a DNA vaccine encoding the ST antigen to generate an antitumor effect in a murine tumor model expressing ST.

We have generated the first BRI2 Danish Knock-In (FDDKI) murine model of FDD, expressing the pathogenic decamer duplication in exon 6 of the BRI2 gene.

In a murine model only CXCR4 expressing, but not CXCR4-deficient CT-26 colon carcinoma cells grew into macrometastases; nonetheless both cell types were able to colonise livers and lungs after injection (Zeelenberg et al, 2003).

The R6/2 transgenic mouse model for HD is a well-established murine model that expresses mutant human Huntingtin exon1 having 150 CAG repeats.

Except for the PS1 model, these murine models of AD typically express sufficiently high levels of hAPP and Aβ to insure amyloid deposition.