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LTP was reduced and LTD was augmented in comparison to diploid controls in the isolated hippocampus of Ts65Dn and Ts1Cje, two DS murine models carrying a partial trisomy 16 encompassing the DYRK1A gene [38], [39], [40].
From 1950s to 1970s syngeneic murine models were used.
Twelve studies were performed using murine models.
Moreover, ablation of glial cells instigated enterocolitis in murine models.
Several studies described the presence of tumor-associated neutrophils (TAN) in murine models.
Other human studies and murine models of myocardial infarction support these findings [50-53] [50-53]
It was validated against Lewis lung carcinoma cells in murine models.
It has shown efficacy in murine models and single human case reports of alcohol withdrawal [22 25].
Murine models of cardiovascular disease are increasingly important for evaluation of novel therapeutic approaches.
Murine models of IL-9 overexpression showed pulmonary infiltration, airway inflammation, and bronchial hyperresponsiveness.
A similar clinical presentation of hypodynamic shock is seen in most murine models [76 78].
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