Sentence examples for murine models demonstrate from inspiring English sources

Murine models demonstrate that C5a exerts an anti-inflammatory effect in pancreatitis [ 36], but, to date, there is only limited evidence for the use of C1 INH in acute pancreatitis [ 35].

The associations found in humans and the empirical evidence from murine models demonstrate that further research into the immunomodulatory role of NK cells in autoimmunity is warranted and is likely to provide novel insights into the pathogenesis of autoimmune disorders.

As murine models demonstrate that especially DC are effective in inducing effective immune responses, ex vivo generated DC are currently applied to stimulate anti-tumour immunity in clinical trials (Banchereau et al, 2000; Coulie and van der Bruggen, 2003; De Vries et al, 2003; Schuler et al, 2003; Figdor et al, 2004).

Evaluation of effects of NM on xenografts in murine models demonstrated significant reduction in tumor size and tumor burden in all human cancer cell lines tested.

Accumulating evidence from murine models demonstrated that the infiltration of monocytes into the liver is a major pathogenic factor for chronic hepatic inflammation and fibrosis [ 3- 6].

Concordantly, recent studies in an ischemia-reperfusion murine model demonstrate that preventing the rise in intrarenal pressure caused by interstitial edema by making a small incision in renal capsule attenuates the risk of functional renal impairment.

Subsequently, in vivo studies using a murine model demonstrated the biocompatibility of the different fish scale-derived collagen patches.

This murine model demonstrates the utility of microsurgical techniques to study in vivo cardiac physiology in transgenic mice and should allow the application of genetic approaches to identify the mechanisms that activate ventricular expression of the ANF gene during in vivo hypertrophy.

More recently, several studies in the murine model demonstrated that dysfunctional CFTR might alter the bactericidal activity of alveolar macrophages, further contributing to the poor control of bacterial growth in CF patients [12] [14], [20].

This murine model demonstrates several of the critical GBM characteristics such as secondary structures of Scherer and tumour suppressor gene mutations.

Expression of ROL-3 in epidermal tissues is consistent with the murine model, demonstrating the potential for a conserved function between these proteins.